It's a very thorough procedure, partly to make sure he meets the trial eligibility criteria and partly to have a baseline against which any changes to his body arising from the drugs or their side effects can be measured.
So - what was involved?
- Physical examination, including height and weight measurements
- Vital signs (blood pressure, pulse rate and temperature)
- Blood tests
- Urine tests
- ECG (heart trace - three tracings over 5-10 minutes)
- Echocardiogram (a bit like an ultrasound scan, with jelly on the chest )
- Eye test - to rule out any eye conditions that might be made worse taking the study treatment
The tests themselves were relatively straightforward. It was only the very thorough eye tests, which involved dilating the pupils, which caused any problems. Even though it was cloudy, the brightness on going outside after the test hurt Steve's eyes. But he was back to normal by the time we arrived home....Must remember to take sunglasses or a baseball cap next time to shade his eyes!
Only when they check the results of all these tests will we know if Steve can take part in the trial.